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Draft:Iteos therapeutics

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iTeos Therapeutics

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Overview

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iTeos Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery and development of immuno-oncology therapeutics. The company is headquartered in Watertown, Massachusetts, United States, with additional operations in Gosselies, Belgium. Founded in 2012 as a spin-off from the Ludwig Institute for Cancer Research and de Duve Institute at the Université catholique de Louvain, iTeos aims to leverage insights into tumor biology and immunology to advance cancer treatments.[1].

History

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iTeos was established by Michel Detheux and Benoit Van den Eynde, both of whom are researchers specializing in immuno-oncology. Initially, the company focused on preclinical research and drug discovery, and it later transitioned to clinical development following the identification of key therapeutic candidates.

In July 2020, iTeos completed its initial public offering (IPO) and began trading on the NASDAQ stock exchange under the ticker symbol "ITOS." The IPO raised approximately $201 million to support the development of its clinical programs and expand its pipeline [2].

Collaborations

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In June 2021, iTeos announced a collaboration with GlaxoSmithKline (GSK) to co-develop and commercialize EOS-448 (an anti-TIGIT drug). The partnership involved an upfront payment of $625 million to iTeos, with additional milestone payments and royalties. This collaboration is intended to accelerate the clinical development of EOS-448 by leveraging GSK’s global resources and expertise [3]

References

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