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Draft:Joel H. Rothman

From Wikipedia, the free encyclopedia
Joel Rothman
NationalityAmerican
OccupationMolecular biologist
Known for
  • Research on embryonic development in Caenorhabditis elegans
  • Regulation of development, differentiation, and programmed cell death
TitleDistinguished Professor, Wilcox Family Chair in Biotechnology
Awards
  • Searle Scholars Award
  • Shaw Scientists Award
Academic background
Alma materUniversity of Oregon (Ph.D.)
Academic work
DisciplineMolecular, Cellular, and Developmental Biology
InstitutionsUniversity of California, Santa Barbara

Joel H. Rothman an American molecular biologist and developmental biologist who serves as the Professor and Wilcox Family Chair in Biotechnology at the University of California, Santa Barbara (UCSB). He is known for his research on embryonic development, specifically on his work on the nematode Caenorhabditis elegans. His research focuses on the regulation of cellular processes such as differentiation, division, and programmed cell death, contributing to the understanding of developmental biology and tumorigenesis. He received the Shaw Scientists Award and founded UCSB's Center for Aging and Longevity Studies.[1][2]

Education and background

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Rothman got a Bachelor degree from the University of California, Davis. He graduated with a Ph.D. from the University of Oregon.

Career and research

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Selected publications

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  • Rothman, Joel H., Carl T. Yamashiro, Christopher K. Raymond, Patricia M. Kane, and Tom H. Stevens. "Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins." The Journal of cell biology 109, no. 1 (1989): 93-100.
  • Derry, W. Brent, Aaron P. Putzke, and Joel H. Rothman. "Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance." Science 294, no. 5542 (2001): 591-595.
  • Rothman, Joel H., and Tom H. Stevens. "Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway." Cell 47, no. 6 (1986): 1041-1051.
  • PEP4 Gene of Saccharomyces cerevisiae Encodes Proteinase A, a Vacuolar Enzyme Required for Processing of Vacuolar Precursors
  • Valls, Luis A., Craig P. Hunter, Joel H. Rothman, and Tom H. Stevens. "Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide." Cell 48, no. 5 (1987): 887-897.
  • Raich, William B., Adrienne N. Moran, Joel H. Rothman, and Jeff Hardin. "Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin-like protein ZEN-4." Molecular biology of the cell 9, no. 8 (1998): 2037-2049.
  • Rothman, Joel H., Christopher K. Raymond, Teresa Gilbert, Patrick J. O'Hara, and Tom H. Stevens. "A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting." Cell 61, no. 6 (1990): 1063-1074.

References

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  1. ^ "Joel Rothman | Joel Rothman Lab | UC Santa Barbara". labs.mcdb.ucsb.edu. Retrieved 2025-01-06.
  2. ^ "Sending Life to the Stars: Scientists Contemplate Launching Tiny Lifeforms Into Interstellar Space". SciTechDaily. 2022-01-08. Retrieved 2025-01-06.