Talk:Histamine intolerance/GA1

GA Review

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Nominator: Maxim Masiutin (talk · contribs) 17:12, 29 December 2024 (UTC)[reply]

Reviewer: IntentionallyDense (talk · contribs) 04:24, 5 January 2025 (UTC)[reply]

I'll review this shortly. IntentionallyDense ^(Contribs) 04:24, 5 January 2025 (UTC)[reply]

Rate	Attribute	Review Comment
1. Well-written:
	1a. the prose is clear, concise, and understandable to an appropriately broad audience; spelling and grammar are correct.
	1b. it complies with the Manual of Style guidelines for lead sections, layout, words to watch, fiction, and list incorporation.
2. Verifiable with no original research, as shown by a source spot-check:
	2a. it contains a list of all references (sources of information), presented in accordance with the layout style guideline.	ref list exists. IntentionallyDense ^(Contribs) 02:26, 7 January 2025 (UTC)[reply]
	2b. reliable sources are cited inline. All content that could reasonably be challenged, except for plot summaries and that which summarizes cited content elsewhere in the article, must be cited no later than the end of the paragraph (or line if the content is not in prose).	I checked [1][2][3][4][5] and they were all good. There is a minor issue with one of the refs which I highlighted below. IntentionallyDense ^(Contribs) 05:27, 8 January 2025 (UTC)[reply]
	2c. it contains no original research.	IntentionallyDense ^(Contribs) 05:27, 8 January 2025 (UTC)[reply]
	2d. it contains no copyright violations or plagiarism.	IntentionallyDense ^(Contribs) 05:27, 8 January 2025 (UTC)[reply]
3. Broad in its coverage:
	3a. it addresses the main aspects of the topic.
	3b. it stays focused on the topic without going into unnecessary detail (see summary style).
	4. Neutral: it represents viewpoints fairly and without editorial bias, giving due weight to each.
	5. Stable: it does not change significantly from day to day because of an ongoing edit war or content dispute.	stable. IntentionallyDense ^(Contribs) 02:26, 7 January 2025 (UTC)[reply]
6. Illustrated, if possible, by media such as images, video, or audio:
	6a. media are tagged with their copyright statuses, and valid non-free use rationales are provided for non-free content.
	6b. media are relevant to the topic, and have suitable captions.
	7. Overall assessment.

I feel like you could at least add some images here of either symptoms (such as flushing etc) or even a photo of histamine in the causes section. IntentionallyDense ^(Contribs) 02:26, 7 January 2025 (UTC)[reply]
I don't think the lead here best represents the article. Take a look at Wikipedia:How to create and manage a good lead section. Specifically I'd expect a little bit of a longer lead and possibly written in a way that doesn't need citations. IntentionallyDense ^(Contribs) 02:26, 7 January 2025 (UTC)[reply]
@IntentionallyDense i tried to work out a longer lead as I typically do for other articles that I edit, but for this one I didn't have ideas. Do you have a suggestion besides what is given in WP:LEAD ? Maxim Masiutin (talk) 08:27, 8 January 2025 (UTC)[reply]
I’ll get back to you on this one once I’ve read through the entire article but it may just be that one paragraph is appropriate. IntentionallyDense ^(Contribs) 19:02, 8 January 2025 (UTC)[reply]
The one bare URL should be fixed as these are prone to link rot. IntentionallyDense ^(Contribs) 02:26, 7 January 2025 (UTC)[reply]
I replaced that bare reference with "cite news", and added "archive-url" attribute to each "cite" where there was an "url" attribute. Maxim Masiutin (talk) 08:50, 8 January 2025 (UTC)[reply]
ref 25 [6] doesn't verify the info given as it just opens to the ICD 10 search. Is there any way you could link to the actual codes? IntentionallyDense ^(Contribs) 05:27, 8 January 2025 (UTC)[reply]

@IntentionallyDense ok, let me do this in a few days Maxim Masiutin (talk) 08:25, 8 January 2025 (UTC)[reply]

Signs and symptoms

The manifestations of histamine intolerance, or, adverse reactions to ingested histamine, are not confined to the gastrointestinal system, and are usually systemic, affecting the entire body; still, these symptoms are often sporadic and non-specific: symptoms attributed to histamine intolerance are wide-ranging and may affect various physiological systems, including the skin, gastrointestinal, cardiovascular, respiratory, and nervous systems. This sentence is really long and kind of doesn't say much while also using a lot of words. I find myself writing a lot of these kinds of sentences that have a lot of words but don't say much in medical articles. Maybe this could be reworded as Manifestations of histamine intolerance tend to affect multiple organ systems and are often sporadic and non-specefic. adding in more detail as you see fit. Either way I think for readability reasons this sentence needs to be shortened and possibly condensed. IntentionallyDense ^(Contribs) 04:31, 9 January 2025 (UTC)[reply]
Yes, this is a great idea. I just wanted lay persons to understand the meaning, but shortening definitelys help.

I think that we should keep "including the skin, gastrointestinal, cardiovascular, respiratory, and nervous systems".

Maybe we should expand how them manifest in skin (redness, itching), gastrointestinal (gut pain, and manifestation similar to those of irritable bowel syndrome), etc...? Maxim Masiutin (talk) 17:36, 9 January 2025 (UTC)[reply]
I think listing the organ systems is probably a good idea as a lay person may not know exactly what people mean by manifesting in multiple organ systems. And yes the listing symptoms by organ systems would most likely be helpful! IntentionallyDense ^(Contribs) 03:58, 10 January 2025 (UTC)[reply]
These symptoms are not specific to histamine intolerance and may overlap with other conditions or disorders. This overlaps with the nonspecific symptoms part in the last paragraph. I think it may be more beneficial to put this with the other paragraph if at all. IntentionallyDense ^(Contribs) 04:31, 9 January 2025 (UTC)[reply]
Is there any information on symptom onset or duration? Like do people tend to get these symptoms immediately after ingesting certain foods? You mentioned they are sporadic but is there anymore detail on this? IntentionallyDense ^(Contribs) 04:31, 9 January 2025 (UTC)[reply]
There is anecdotal evidence on symptoms onset, but they are not confirmed by reliable reviews or publications such as clinical practice guidelines.

Anecdoatal evidence is that onsets are usually not immediate: it takes time for the histamine intolerance to build it up. This is not an allergy that can be immediately trigger. If a sensitive person eat "bad" food once, it will not happen, probably because enough DAO enzyme accumulated, but on frequent consumption of such food symptoms will show up and then last about 3 month, so that the full elimination diet gives effect in 3 months. That's why it is hard to diagnose. There are food compatibility lists such as SIGHI "Food Compatibility List", these lists are very helpful, but not yet approved by mainstream medical community.

What would you recommend? Maxim Masiutin (talk) 17:40, 9 January 2025 (UTC)[reply]
It could be worth mentioning (keep in mind I haven't read the whole article so I'm not sure if this is mentioned elsewhere) that symptom onset isn't immediate if there is a reliable source to say that. Mostly because even when I think of something like lactose intolerance or non celiac gluten sensitivity, from my understanding, symptom onset is somewhat immediate (like eating dairy and then stomach pain etc). This is more of a suggestion from someone who knows medical articles and not apart of GAN criteria so you can disregard this if it would be a lot of effort to include. IntentionallyDense ^(Contribs) 04:01, 10 January 2025 (UTC)[reply]

Mainstream theory suggests to treat symptoms by excluding the causes. It recommends lifestyle and diet modifications without any specifics what should be modified or eaten. Maxim Masiutin (talk) 17:43, 9 January 2025 (UTC)[reply]
To comply with MOS:LAYOUT I think these two paragraphs should be combined as they are both very short. IntentionallyDense ^(Contribs) 04:31, 9 January 2025 (UTC)[reply]

Causes

Would you be opposed to possibly moving the second para of causes (Histamine, a biogenic amine found in various food products) to be the first para? I mention this because it seems to be more of an introduction to the causes then the current first paragraph. Also the third paragraph goes into more detail on the theory presented in the first para. IntentionallyDense ^(Contribs) 04:14, 10 January 2025 (UTC)[reply]
A small number of studies have attempted to elucidate this relationship through the rigorous methodology of double-blind, placebo-controlled oral food challenges involving histamine. However, the results yielded from these investigations have been notably heterogeneous, further complicating the interpretation of the data. This chunk of text is quite technical. Is there any way you could simplify it a bit by either wikilinking terms (such as placebo) or using more simple terms (such as results being varied instead of heterogeneous). I understand that this topic is going to be technical but this bit seems a bit overly technical for what it is trying to convey. IntentionallyDense ^(Contribs) 04:14, 10 January 2025 (UTC)[reply]
either due to genetic factors, medications, or gastrointestinal diseases I'm going to assume that there isn't any hard evidence on which disorders or medications play a role here? If there is evidence pointing to some disorder or medications it may be worth noting. IntentionallyDense ^(Contribs) 04:14, 10 January 2025 (UTC)[reply]
as well as a positive response to a low-histamine diet, and the treatment of histamine, involves avoiding I'm assuming you meant to put treatment of histamine intolerance here. IntentionallyDense ^(Contribs) 04:14, 10 January 2025 (UTC)[reply]